Inovio Pharmaceuticals Inc (INO) +192.16% stock soared to $1.76 in pre-market trading after announcing that the FDA has granted accelerated approval for VOCERYQ to reduce the need for surgery in adults with RRP.

Perion Network Ltd (NASDAQ: PERI) +30.46% shares are trading up at $11.35 at the time of writing following Affle 3i’s announcement of an all-cash acquisition deal worth approximately $420 million, valuing Perion at $11.70 per share.

22nd Century Group Inc (XXII) +26.01% grew to $0.09 in pre-market trading today. The company recently announced a trade agreement with Gopuff to offer its Pinnacle VLN® and Pinnacle Pure products through app-based direct-to-consumer delivery.

Primech Holdings Ltd (PMEC) +20.03% jumped to $0.42 in pre-market trading Monday. The company, through its subsidiary Primech AI, secured a contract worth over US$60,000 to supply one HYTRON autonomous restroom-cleaning robot and provide four years of maintenance services to a retail mall in Singapore.

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Jefferies turned bullish on Rivian Automotive Inc (RIVN) BUY, upgrading the stock and assigning a $17 price target, representing potential upside of 39.80% from Sunday's close.

GE Vernova Inc (GEV) has won the favor of HSBC Securities' equity research team. The firm upgraded the shares from Hold to BUY and moved its price target to $1,100, suggesting 28.22% additional upside for the stock.

Monolithic Power Systems Inc (MPWR) received an upgrade from analysts at Rosenblatt, who also set their one-year price target on the stock to $1,700. They changed their rating on MPWR to BUY from Neutral in a recently issued research note.

Roth Capital reduced its rating on Intel Corp (INTC) stock to NEUTRAL from Buy and assigned the price target to $70.

Stifel analysts reduced their investment ratings, saying in research reports covered by the media that its rating for Acumen Pharmaceuticals Inc (ABOS) has been changed to HOLD from Buy and the new price target is set at $1.

Analysts at RBC Capital Mkts downgraded Medical Properties Trust Inc (MPT) stock to UNDERPERFORM from Sector Perform, and the new price target is set at $2.

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Vale SA (VALE) BUY — Accounting Officer, de Souza Funo Elaine Maria declared the purchase of shares taking place on Oct 26 '26 at $11.74 for some 7 shares. The transaction amount was around $82.

Redcloud Holdings PLC (RCT) BUY — Director, Senn Nikolaus Beat bought on Oct 28 '26 a total of 1700000 shares at $0.25 on average. The purchase cost the insider an estimated $425,000.

CoreWeave Inc (CRWV) SELL — Principal Accounting Officer, Baker Jeff, announced the sale of shares taking place on Oct 29 '26 at $61.16 for some 6670 shares. The total came to more than $407,947.

Alphabet Inc Class C (GOOG) SELL — Director, ARNOLD FRANCES sold on Oct 29 '26 a total 82 shares at $284 on average. The insider’s sale generated proceeds of almost $23,288.

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Top US earnings releases scheduled for today include Apple Inc (AAPL). It will announce its September 2026 financial results. The company is expected to report earnings of $1.98 per share from revenues of $113.27B in the three-month period.

Analysts expect Grab Holdings Ltd (GRAB) to report a net income (adjusted) of $0.02 per share when the company releases its quarterly results shortly. Revenue for the fiscal quarter ended September 2026 is predicted to come in at $1.1B.

Transocean LTD (RIG), due to announce earnings after the market closes today, is expected to report earnings of $0.02 per share on revenues of $942.29M for the recently concluded three-month period.